Antiproliferative agent-42
Antiproliferative agent-42 (compound 7m) is a dihydrodipyrrolo compound. Antiproliferative agent-42 showed antiproliferative activity against Panc-1 cell line with an IC50 value of 12.54 μM[1].
Product Specifications
CAS Number
3002404-74-9
UNSPSC
12352005
Target
Apoptosis; Caspase
Type
Reference compound
Related Pathways
Apoptosis
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/antiproliferative-agent-42.html
Solubility
10 mM in DMSO
Smiles
O=C1NNC(C2=C1C(C3=CC([N+]([O-])=O)=CC=C3)=C4N2CCN5C4=CC=C5)=O
Molecular Formula
C18H13N5O4
Molecular Weight
363.33
References & Citations
[1]Lish A B, et al. Synthesis and Biological Evaluation of 12-Aryl-11-hydroxy-5,6-dihydropyrrolo[2″,1″:3′,4′]pyrazino[1′,2′:1,5]pyrrolo[2,3‑d]pyridazine-8 (9H) ‑one Derivatives as Potential Cytotoxic Agents [J].[2023-11-08].|[2]Barghi Lish, Azam, et al. "Synthesis and Biological Evaluation of 12-Aryl-11-hydroxy-5, 6-dihydropyrrolo [2 ″, 1 ″: 3′, 4′] pyrazino [1′, 2′: 1, 5] pyrrolo [2, 3-d] pyridazine-8 (9 H) -one Derivatives as Potential Cytotoxic Agents." ACS Omega (2023) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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