PRO-HD3
PRO-HD3 is a cell-specific, PROTAC-based HDAC6 degrader[1].
Product Specifications
UNSPSC
12352005
Target
HDAC; PROTACs
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pro-hd3.html
Solubility
10 mM in DMSO
Smiles
S=C1N(CC2=CC=C(C3=CC=C(CNCCCCCCCCNC4=CC=CC(C(N5C6CCC(NC6=O)=O)=O)=C4C5=O)C=C3)C=C2)C=CC=C1O
Molecular Formula
C40H43N5O5S
Molecular Weight
705.86
References & Citations
[1]Qi Jia, et al. Cell-Specific Degradation of Histone Deacetylase Using Warhead-Caged Proteolysis Targeting Chimeras. Anal Chem. 2023 Oct 30.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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