PRO-HD2
Product Specifications
UNSPSC Description
PRO-HD2 is a cell-specific, PROTAC-based HDAC6 degrader[1].
Target Antigen
HDAC; PROTACs
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Epigenetics;PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pro-hd2.html
Solubility
10 mM in DMSO
Smiles
S=C1N(CC2=CC=C(C3=CC=C(CNCCCCCCNC4=CC=CC(C(N5C6CCC(NC6=O)=O)=O)=C4C5=O)C=C3)C=C2)C=CC=C1O
Molecular Weight
677.81
References & Citations
[1]Qi Jia, et al. Cell-Specific Degradation of Histone Deacetylase Using Warhead-Caged Proteolysis Targeting Chimeras. Anal Chem. 2023 Oct 30.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-155397/PRO-HD2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-155397/
Clinical Information
No Development Reported
Curated Selection
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