PROTAC BRD4 Degrader-22
PROTAC BRD4 Degrader-22 (Compd 44h) is a PROTAC-based BRD4 degrader, with a pDC50 (MOLT4, 24 h) of 9.2[1].
Product Specifications
CAS Number
3032850-37-3
UNSPSC
12352005
Target
Epigenetic Reader Domain; PROTACs
Type
Reference compound
Related Pathways
Epigenetics; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-brd4-degrader-22.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C(C=C1OC)N2CCC(CC2)CNC(C[C@@H]3N=C(C4=C(N5C(C)=NN=C35)SC(C)=C4C)C6=CC=C(C=C6)Cl)=O)NC(C(N7)=O)CCC7=O
Molecular Formula
C38H41ClN8O5S
Molecular Weight
757.30
References & Citations
[1]Christian Steinebach, et al. Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs. J Med Chem. 2023 Oct 30.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
RG239854 10 µg
Pumilio 2 (PUM2) (NM_001282790) Human Tagged ORF Clone
Sign In for Pricing
View Details ![Purified Anti-Human CD32 Antibody[IV-3]](https://cdn.genprice.uk/products/763/68dd14c4061270361e7d7157/imageurl/e-ab-f1075a.webp)
