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β-Herpesvirus protease-IN-1

Product Specifications

UNSPSC Description

β-Herpesvirus protease-IN-1 (compound 19) is a β-herpesvirus protease inhibitor with IC50s of 2.5 μM and 0.33 μM for HCMVPro and HHV6Pro, respectively[1].

Target Antigen

Virus Protease

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/β-herpesvirus-protease-in-1.html

Solubility

10 mM in DMSO

Smiles

O=C1N([C@H](CN1C2=CC=CN(C2=O)[C@H](C3=CN(N=C3C4=C(C=CC=C4)C)C5CCCC5)C6=CC=C(C=C6)C)C(NC78C(NC(CC8)CC7)=O)=O)C

Molecular Weight

687.83

References & Citations

[1]Shuhei Yoshida, et al. Peptide-to-Small Molecule: Discovery of Non-Covalent, Active-Site Inhibitors of β-Herpesvirus Proteases. ACS Med. Chem. Lett.October 27, 2023.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-155379/β-Herpesvirus-protease-IN-1-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-155379/

Clinical Information

No Development Reported

Curated Selection

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