β-Herpesvirus protease-IN-1

β-Herpesvirus protease-IN-1 (compound 19) is a β-herpesvirus protease inhibitor with IC50s of 2.5 μM and 0.33 μM for HCMVPro and HHV6Pro, respectively[1].

Product Specifications

UNSPSC

12352005

Target

Virus Protease

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/β-herpesvirus-protease-in-1.html

Solubility

10 mM in DMSO

Smiles

O=C1N([C@H](CN1C2=CC=CN(C2=O)[C@H](C3=CN(N=C3C4=C(C=CC=C4)C)C5CCCC5)C6=CC=C(C=C6)C)C(NC78C(NC(CC8)CC7)=O)=O)C

Molecular Formula

C40H45N7O4

Molecular Weight

687.83

References & Citations

[1]Shuhei Yoshida, et al. Peptide-to-Small Molecule: Discovery of Non-Covalent, Active-Site Inhibitors of β-Herpesvirus Proteases. ACS Med. Chem. Lett.October 27, 2023.