MTOR inhibitor-14
MTOR inhibitor-14 (compound 14c) is a potent mTOR inhibitor. mTOR inhibitor-14 also shows minimal CYP2C8 inhibition. mTOR inhibitor-14 can inhibit tumor growth[1].
Product Specifications
UNSPSC
12352005
Target
MTOR
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mtor-inhibitor-14.html
Solubility
10 mM in DMSO
Smiles
O[C@H](CC1)CC[C@@H]1N(C2=CN=C(C3=CC=CC4=C3C=CN4)N=C2N5[C@@]6(C)COCC5)C6=O
Molecular Formula
C24H27N5O3
Molecular Weight
433.50
References & Citations
[1]Sean T. Murphy, et al. Optimization of mTOR Inhibitors Using Property-Based Drug Design and Free–Wilson Analysis for Improved In Vivo Efficacy. ACS Med. Chem. Lett. 2023.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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