mTOR inhibitor-14
Product Specifications
UNSPSC Description
mTOR inhibitor-14 (compound 14c) is a potent mTOR inhibitor. mTOR inhibitor-14 also shows minimal CYP2C8 inhibition. mTOR inhibitor-14 can inhibit tumor growth[1].
Target Antigen
mTOR
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mtor-inhibitor-14.html
Solubility
10 mM in DMSO
Smiles
O[C@H](CC1)CC[C@@H]1N(C2=CN=C(C3=CC=CC4=C3C=CN4)N=C2N5[C@@]6(C)COCC5)C6=O
Molecular Weight
433.50
References & Citations
[1]Sean T. Murphy, et al. Optimization of mTOR Inhibitors Using Property-Based Drug Design and Free–Wilson Analysis for Improved In Vivo Efficacy. ACS Med. Chem. Lett. 2023.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-155376/mTOR-inhibitor-14-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-155376/
Clinical Information
No Development Reported
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