IR808-TZ

IR808-TZ is a Tetraazine base station shipped with. IR808-TZ is a biocompatible PROTAC (BT-PROTAC) that can activate MZ1 and reduce BRD4 specificity[1].

Product Specifications

UNSPSC

12352005

Target

PROTACs

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ir808-tz.html

Solubility

10 mM in DMSO

Smiles

CC1(C(/C=C/C(CCC/C2=C\C=C3N(C4=C(C\3(C)C)C=CC=C4)CCCCCC(NCC5=NN=C(N=N5)C)=O)=C2Cl)=[N+](C6=CC=CC=C61)CCCCCC(O)=O)C.F[P-](F)(F)(F)(F)F

Molecular Formula

C46H57ClF6N7O3P

Molecular Weight

936.41

References & Citations

[1]Tao Bi, et al. Rational Design of Bioorthogonally Activatable PROTAC for Tumor-Targeted Protein Degradation. J Med Chem . 2023 Oct 23.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

A10169-50UG 50 µg

mOrange Monoclonal Antibody

Ask

View Details

NBP3-14002PCP 0.1 mL

Rabbit Monoclonal RBFOX3/NeuN Antibody (NeuN/288R) [PerCP]

Ask

View Details

NBP3-06404MFV500 0.1 mL

Rabbit Polyclonal RABEP2 Antibody [mFluor Violet 500 SE]

Ask

View Details

A24980-50UL 50 μL

2-hydroxyisobutyryl-HIST1H3A (K122) Antibody

Ask

View Details

MR219196L4V 200 µL

Yif1b (NM_029887) Mouse Tagged ORF Clone Lentiviral Particle

Ask

View Details