AChE-IN-45
AChE-IN-45 (Compound 14) is an acetylcholinesterase (AChE) inhibitor with IC50 of 11.57±0.45 nM that shows antioxidant and neuroprotective activities[1].
Product Specifications
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ache-in-45.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=NC=CN=C1)CSC(N2C3=CC=C(S(=O)(N)=O)C=C3)=NC4=C(C=C(I)C=C4)C2=O
Molecular Formula
C20H15IN6O4S2
Molecular Weight
594.41
References & Citations
[1]Aiten M Soliman, et al. Novel iodoquinazolinones bearing sulfonamide moiety as potential antioxidants and neuroprotectors. Sci Rep. 2023 Sep 20;13 (1) :15546.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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