AB131

AB131 is a MSMEG 6649 and Rv2172c inhibitor (Kd: 0.16 and 0.02 μM respectively) . AB131 can sensitize the antimycobacterial activity of the antitubercular agent[1].

Product Specifications

CAS Number

[720671-77-2]

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/ab131.html

Solubility

10 mM in DMSO

Smiles

O=C(OCSCCC(N1C(C(C=CC=C2)=C2C1=O)=O)C(OC)=O)C3=CC=CC=C3

Molecular Formula

C21H19NO6S

Molecular Weight

413.44

References & Citations

[1]Li J, et al. Identification of a Potential Antimycobacterial Drug Sensitizer Targeting a Flavin-Independent Methylenetetrahydrofolate Reductase. ACS Omega. 2023 Oct 4;8 (41) :38406-38417.