AB131
Product Specifications
UNSPSC Description
AB131 is a MSMEG 6649 and Rv2172c inhibitor (Kd: 0.16 and 0.02 μM respectively). AB131 can sensitize the antimycobacterial activity of the antitubercular agent[1].
Target Antigen
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ab131.html
Solubility
10 mM in DMSO
Smiles
O=C(OCSCCC(N1C(C(C=CC=C2)=C2C1=O)=O)C(OC)=O)C3=CC=CC=C3
Molecular Weight
413.44
References & Citations
[1]Li J, et al. Identification of a Potential Antimycobacterial Drug Sensitizer Targeting a Flavin-Independent Methylenetetrahydrofolate Reductase. ACS Omega. 2023 Oct 4;8(41):38406-38417.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-155332/AB131-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-155332/
Clinical Information
No Development Reported
CAS Number
720671-77-2
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