AB131
AB131 is a MSMEG 6649 and Rv2172c inhibitor (Kd: 0.16 and 0.02 μM respectively) . AB131 can sensitize the antimycobacterial activity of the antitubercular agent[1].
Product Specifications
CAS Number
[720671-77-2]
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ab131.html
Solubility
10 mM in DMSO
Smiles
O=C(OCSCCC(N1C(C(C=CC=C2)=C2C1=O)=O)C(OC)=O)C3=CC=CC=C3
Molecular Formula
C21H19NO6S
Molecular Weight
413.44
References & Citations
[1]Li J, et al. Identification of a Potential Antimycobacterial Drug Sensitizer Targeting a Flavin-Independent Methylenetetrahydrofolate Reductase. ACS Omega. 2023 Oct 4;8 (41) :38406-38417.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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