Tubulin polymerization-IN-51
Tubulin polymerization-IN-51 (compound 7u) is a tubulin polymerization inhibitor with IC50 value of 2.55 - 17.89μM for SK-Mel-28 cells. Tubulin polymerization-IN-51 can be used for cancer research[1].
Product Specifications
CAS Number
[2998928-27-9]
UNSPSC
12352005
Target
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tubulin-polymerization-in-51.html
Solubility
10 mM in DMSO
Smiles
COC1=CC(C2=NC3=C(N2)C=CC(C)=C3)=CC=C1OCC(N4CC5=C(C=CC=C5)CC4)=O
Molecular Formula
C26H25N3O3
Molecular Weight
427.50
References & Citations
[1]Laxmikeshav K, et al. Benzimidazole derivatives as tubulin polymerization inhibitors: Design, synthesis and in vitro cytotoxicity studies. Bioorg Med Chem Lett. 2023 Oct 3;96:129494.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
P4073-34J-AP 100 µL
Phosphoinositide 3 Kinase, p110 delta (CT) (p110D, p110delta, Phosphatidylinositol 3 Kinase Catalytic delta Polypeptide, Phosphatidylinositol-4,5-bisphosphate 3-kinase Catalytic Subunit delta Isoform, Phosphoinositide 3 Kinase B, Phosphoinositide 3 Kinase C, Phosphoinositide 3 Kinase Catalytic delta Polypeptide, P13-kinase p110 delta, PI3-kinase p110 Subunit delta, PI3K, PIK3CD, PtdIns-3-kinase p110) (AP) discontinued
Ask
View Details 
MBS647037-01 0.1 mg
NHLRC1 (E3 Ubiquitin-protein Ligase NHLRC1, Malin, NHL Repeat-containing Protein 1, EPM2B, MGC119262, MGC119264, MGC119265)
Ask
View Details MBS647037-02 5x 0.1 mg
NHLRC1 (E3 Ubiquitin-protein Ligase NHLRC1, Malin, NHL Repeat-containing Protein 1, EPM2B, MGC119262, MGC119264, MGC119265)
Ask
View Details