PITB
Product Specifications
UNSPSC Description
PITB is a selective and orally active transthyretin (TTR) aggregation inhibitor. PITB can be used for transthyretin amyloidosis (ATTR) disease research[1].
Target Antigen
Transthyretin (TTR)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pitb.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(O)=CC(F)=C1)C2=CC(OC)=C(O)C([N+]([O-])=O)=C2
Molecular Weight
307.23
References & Citations
[1]Francisca Pinheiro, et al. PITB: A high affinity transthyretin aggregation inhibitor with optimal pharmacokinetic properties. Eur J Med Chem. 2023 Oct 6:261:115837.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-155299/PITB-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-155299/
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Rat Monoclonal M-CSFR/CD115 Antibody (460615) [Janelia Fluor 585]](https://cdn.genprice.uk/genprice/genprice2.png)
FAB3818JF585 0.1 mL
Rat Monoclonal M-CSFR/CD115 Antibody (460615) [Janelia Fluor 585]
Ask
View Details 
MBS1420019-01 0.02 mg (E-Coli)
Recombinant Sulfolobus islandicus filamentous virus Uncharacterized protein 64 (SIFV0064)
Ask
View Details MBS1420019-02 0.1 mg (E-Coli)
Recombinant Sulfolobus islandicus filamentous virus Uncharacterized protein 64 (SIFV0064)
Ask
View Details 
MBS1420019-03 0.02 mg (Yeast)
Recombinant Sulfolobus islandicus filamentous virus Uncharacterized protein 64 (SIFV0064)
Ask
View Details 
MBS1420019-04 0.1 mg (Yeast)
Recombinant Sulfolobus islandicus filamentous virus Uncharacterized protein 64 (SIFV0064)
Ask
View Details MBS1420019-05 0.02 mg (Baculovirus)
Recombinant Sulfolobus islandicus filamentous virus Uncharacterized protein 64 (SIFV0064)
Ask
View Details