K1833
K1833 is a hrAChE inhibitor/reactivator, with an IC50 of 58 μM. K1833 also shows high inhibition (IC50=0.57μM) and low reactivation for hrBChE[1].
Product Specifications
UNSPSC
12352211
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/k1833.html
Solubility
10 mM in DMSO
Smiles
FB1(F)N2C=CC=C2C(NCCNC(C3=CC=[N+](CCC[N+]4=CC=C(/C=N/O)C=C4)C=C3)=O)=C5C=CC=[N]15.[Br-].[Br-]
Molecular Formula
C26H28BBr2F2N7O2
Molecular Weight
679.16
References & Citations
[1]Prchalova E, et, al. BODIPY-labelled acetylcholinesterase reactivators can be encapsulated into ferritin nanovehicles for enhanced bioavailability in the CNS. Biomed Pharmacother. 2023 Nov:167:115490.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE; BChE
Curated Selection
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