FASN-IN-6
FASN-IN-6 (compound 44) is a potent fatty acid biosynthesis (FAB) inhibitor. FASN-IN-6 is an antibacterial agent with MICs of 1 μg/mL and 4 μg/mL for S. aureus ATCC 25923 and E. faecalis ATCC 29212, respectively[1].
Product Specifications
CAS Number
[3032387-88-2]
UNSPSC
12352005
Target
Bacterial; Fatty Acid Synthase (FASN)
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/fasn-in-6.html
Solubility
10 mM in DMSO
Smiles
O=C(O)C1=CC=C(N2N=C(C3=CC=CC(F)=C3)C(CNC4=CC=C(Br)C(C(F)(F)F)=C4)=C2)C=C1
Molecular Formula
C24H16BrF4N3O2
Molecular Weight
534.30
References & Citations
[1]Subrata Roy, et al. Development and Antibacterial Properties of 4-[4- (Anilinomethyl) -3-phenylpyrazol-1-yl]benzoic Acid Derivatives as Fatty Acid Biosynthesis Inhibitors. J Med Chem. 2023 Oct 12;66 (19) :13622-13645.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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