FASN-IN-6

FASN-IN-6 (compound 44) is a potent fatty acid biosynthesis (FAB) inhibitor. FASN-IN-6 is an antibacterial agent with MICs of 1 μg/mL and 4 μg/mL for S. aureus ATCC 25923 and E. faecalis ATCC 29212, respectively[1].

Product Specifications

CAS Number

[3032387-88-2]

UNSPSC

12352005

Target

Bacterial; Fatty Acid Synthase (FASN)

Type

Reference compound

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/fasn-in-6.html

Solubility

10 mM in DMSO

Smiles

O=C(O)C1=CC=C(N2N=C(C3=CC=CC(F)=C3)C(CNC4=CC=C(Br)C(C(F)(F)F)=C4)=C2)C=C1

Molecular Formula

C24H16BrF4N3O2

Molecular Weight

534.30

References & Citations

[1]Subrata Roy, et al. Development and Antibacterial Properties of 4-[4- (Anilinomethyl) -3-phenylpyrazol-1-yl]benzoic Acid Derivatives as Fatty Acid Biosynthesis Inhibitors. J Med Chem. 2023 Oct 12;66 (19) :13622-13645.