Antiparasitic agent-18
Antiparasitic agent-18 (compound 3a) is active and selective against the T. brucei (EC50=0.4 μM), T. cruzi (EC50=0.21 μM), and L. donovani (EC50=0.26 μM) . Antiparasitic agent-18 has potent antiprotozoal activity[1].
Product Specifications
CAS Number
2821884-59-5
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antiparasitic-agent-18.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=C(NC(C2=NC=CC=C2)=N)C=C1)C3=CC=C(NC(C4=NC=CC=C4)=N)C=C3
Molecular Formula
C25H21N7O
Molecular Weight
435.48
References & Citations
[1]J Jonathan Nué-Martinez, et al. Synthesis and Biophysical and Biological Studies of N-Phenylbenzamide Derivatives Targeting Kinetoplastid Parasites. J Med Chem. 2023 Oct 12;66 (19) :13452-13480.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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