SHP2-IN-19
SHP2-IN-19 (compound 183) is a SHP2 inhibitor with an IC50 value of 3 nM. SHP2-IN-19 can be used for glioblastoma research[1].
Product Specifications
CAS Number
[2941498-84-4]
UNSPSC
12352005
Target
SHP2
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/shp2-in-19.html
Solubility
10 mM in DMSO
Smiles
CC1=C(N2C(C(N3CCC4(CC(N=CC=C5)=C5[C@H]4N)CC3)=N1)=CC=N2)C6=CC(OCCO7)=C7C=C6
Molecular Formula
C27H28N6O2
Molecular Weight
468.55
References & Citations
[1]Sabnis RW. Novel Pyrazolopyrazine Compounds as SHP2 Inhibitors for Treating Glioblastoma. ACS Med Chem Lett. 2023 Sep 19;14 (10) :1336-1337.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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