SHP2-IN-18
Product Specifications
UNSPSC Description
SHP2-IN-18 (compound 183) is a SHP2 inhibitor with an IC50 value of 3 nM. SHP2-IN-18 can be used for glioblastoma research[1].
Target Antigen
SHP2
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/shp2-in-18.html
Solubility
10 mM in DMSO
Smiles
FC1=CC(C)=CC=C1C2=C(C)N=C(N3CCC4(CC(N=CC=C5)=C5[C@H]4N)CC3)C6=CC=NN26
Molecular Weight
442.53
References & Citations
[1]Sabnis RW. Novel Pyrazolopyrazine Compounds as SHP2 Inhibitors for Treating Glioblastoma. ACS Med Chem Lett. 2023 Sep 19;14(10):1336-1337.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-155274/SHP2-IN-18-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-155274/
Clinical Information
No Development Reported
CAS Number
2941498-87-7
Curated Selection
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