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SHP2-IN-18

SHP2-IN-18 (compound 183) is a SHP2 inhibitor with an IC50 value of 3 nM. SHP2-IN-18 can be used for glioblastoma research[1].

Product Specifications

CAS Number

2941498-87-7

UNSPSC

12352005

Target

SHP2

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/shp2-in-18.html

Solubility

10 mM in DMSO

Smiles

FC1=CC(C)=CC=C1C2=C(C)N=C(N3CCC4(CC(N=CC=C5)=C5[C@H]4N)CC3)C6=CC=NN26

Molecular Formula

C26H27FN6

Molecular Weight

442.53

References & Citations

[1]Sabnis RW. Novel Pyrazolopyrazine Compounds as SHP2 Inhibitors for Treating Glioblastoma. ACS Med Chem Lett. 2023 Sep 19;14 (10) :1336-1337.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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