SHP2-IN-16
SHP2-IN-16 (compound 222) is a SHP2 inhibitor with an IC50 value of 1 nM. SHP2-IN-16 can be used for glioblastoma research[1].
Product Specifications
UNSPSC
12352005
Target
SHP2
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/shp2-in-16.html
Solubility
10 mM in DMSO
Smiles
FC1=C(F)C=CC=C1C2=C(C)N=C(N3CCC4(CC(N=C(O)C=C5)=C5[C@H]4N)CC3)C6=CC=NN26
Molecular Formula
C25H24F2N6O
Molecular Weight
462.49
References & Citations
[1]Sabnis RW. Novel Pyrazolopyrazine Compounds as SHP2 Inhibitors for Treating Glioblastoma. ACS Med Chem Lett. 2023 Sep 19;14 (10) :1336-1337.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1372866-01 0.02 mg (E-Coli)
Recombinant Human Cytosolic phospholipase A2 epsilon (PLA2G4E) , partial
Ask
View Details MBS1372866-02 0.02 mg (Yeast)
Recombinant Human Cytosolic phospholipase A2 epsilon (PLA2G4E) , partial
Ask
View Details MBS1372866-03 0.1 mg (E-Coli)
Recombinant Human Cytosolic phospholipase A2 epsilon (PLA2G4E) , partial
Ask
View Details MBS1372866-04 0.1 mg (Yeast)
Recombinant Human Cytosolic phospholipase A2 epsilon (PLA2G4E) , partial
Ask
View Details 
MBS1372866-05 0.02 mg (Baculovirus)
Recombinant Human Cytosolic phospholipase A2 epsilon (PLA2G4E) , partial
Ask
View Details