hCAXII-IN-7
Product Specifications
UNSPSC Description
hCAXII-IN-7 (compound 6e) is a hCA XII inhibitor. hCAXII-IN-7 has BBB permeability. hCAXII-IN-7 induces 786-0, SF-539 and HS 578 T cells apoptotic[1].
Target Antigen
Carbonic Anhydrase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/hcaxii-in-7.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=CC=C(N2C=C(/C=N/NC3=CC=C(C(OCC)=O)C=C3)C(C4=CC=C(S(=O)(C)=O)C=C4)=N2)C=C1)(N)=O
Molecular Weight
567.64
References & Citations
[1]Ahmed RF, et al. Exploring novel anticancer pyrazole benzenesulfonamides featuring tail approach strategy as carbonic anhydrase inhibitors. Eur J Med Chem. 2023 Sep 19;261:115805.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-155271/hCAXII-IN-7-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-155271/
Clinical Information
No Development Reported
Curated Selection
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