HCAXII-IN-7

HCAXII-IN-7 (compound 6e) is a hCA XII inhibitor. hCAXII-IN-7 has BBB permeability. hCAXII-IN-7 induces 786-0, SF-539 and HS 578 T cells apoptotic[1].

Product Specifications

UNSPSC

12352005

Target

Carbonic Anhydrase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/hcaxii-in-7.html

Solubility

10 mM in DMSO

Smiles

O=S(C1=CC=C(N2C=C(/C=N/NC3=CC=C(C(OCC)=O)C=C3)C(C4=CC=C(S(=O)(C)=O)C=C4)=N2)C=C1)(N)=O

Molecular Formula

C26H25N5O6S2

Molecular Weight

567.64

References & Citations

[1]Ahmed RF, et al. Exploring novel anticancer pyrazole benzenesulfonamides featuring tail approach strategy as carbonic anhydrase inhibitors. Eur J Med Chem. 2023 Sep 19;261:115805.