Pomalidomide-5-C13-NH2 (hydrochloride)
Pomalidomide-5-C13-NH2 hydrochloride is a Pomalidomide (HY-10984) -based E3 ubiquitin ligase cereblon (CRBN) ligand for recruiting cereblon proteins. Pomalidomide-5-C13-NH2 hydrochloride can be connected to protein ligands through a linker to form PROTAC.
Product Specifications
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pomalidomide-5-c13-nh2-hydrochloride.html
Purity
95.01
Solubility
10 mM in DMSO
Smiles
O=C1C(C=CC(NCCCCCCCCCCCCCN)=C2)=C2C(N1C(CC3)C(NC3=O)=O)=O.Cl
Molecular Formula
C26H39ClN4O4
Molecular Weight
507.07
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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