Pomalidomide-5-C3-NH2 (hydrochloride)
Pomalidomide-5-C3-NH2 hydrochloride is the Pomalidomide (HY-10984) -based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide-5-C3-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC[1].
Product Specifications
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pomalidomide-5-c3-nh2-hydrochloride.html
Purity
96.02
Solubility
10 mM in DMSO
Smiles
O=C1C(C=CC(NCCCN)=C2)=C2C(N1C(CC3)C(NC3=O)=O)=O.Cl
Molecular Formula
C16H19ClN4O4
Molecular Weight
366.80
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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