Anti-TNBC agent-3
Anti-TNBC agent-3 (compound 3g) is an apoptosis inducer with anti-cancer cell proliferation activity. anti-TNBC agent-3 inhibits tumor growth and metastasis in triple-negative breast cancer (TNBC) xenograft models[1].
Product Specifications
CAS Number
2422001-25-8
UNSPSC
12352005
Target
Apoptosis; Bcl-2 Family
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anti-tnbc-agent-3.html
Solubility
10 mM in DMSO
Smiles
OCCN1CCC(C2CCN(C3=NC(N(C4CCCC4)C=N5)=C5C(NCC6=CC(F)=C(F)C=C6)=N3)CC2)CC1
Molecular Formula
C29H39F2N7O
Molecular Weight
539.66
References & Citations
[1]Zhang Q, et al. Synthesis and mechanism of action of new purine derivatives against triple negative breast cancer. Eur J Med Chem. 2023 Sep 7;261:115797.. .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Bcl-2
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