Ancistrotecine B
Ancistrotecine B (Compound 2) is a Nav1.7 channel inhibitor (IC50: 0.73 μM) . Ancistrotecine B relieves inflammatory pain in mice[1].
Product Specifications
UNSPSC
12352005
Target
Sodium Channel
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ancistrotecine-b.html
Solubility
10 mM in DMSO
Smiles
C[C@@H]1N(C)[C@@H](C)C2=C(OC)C(C3=CC=C(O)C4=C3C=C(C)C=C4OC)=C(OC)C=C2C1
Molecular Formula
C26H31NO4
Molecular Weight
421.53
References & Citations
[1]Wang QQ, et al. Naphthylisoquinoline alkaloids, a new structural template inhibitor of Nav1.7 sodium channel. Acta Pharmacol Sin. 2023 Sep;44 (9) :1768-1776.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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