Antileishmanial agent-23
Product Specifications
UNSPSC Description
Antileishmanial agent-23 (compound G1/9) is a potent and selective trypanothione reductase (TR) inhibitor, with an IC50 of 2.24 ± 0.52 μM. Antileishmanial agent-23 inhibits the growth of Leishmania, Trypanosoma cruzi, and Trypanosoma brucei[1].
Target Antigen
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antileishmanial-agent-23.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=C(C=C1)C2=NCC(S2)CSC3=NN=C(C4=CC5=C(OCO5)C=C4)O3
Molecular Weight
427.50
References & Citations
[1]Ilari A, et al. Toward a Drug Against All Kinetoplastids: From LeishBox to Specific and Potent Trypanothione Reductase Inhibitors. Mol Pharm. 2018 Aug 6;15(8):3069-3078.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-155207/Antileishmanial-agent-23-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-155207/
Clinical Information
No Development Reported
CAS Number
9007-83-4
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