SARS-CoV-2 3CLpro-IN-19
Product Specifications
UNSPSC Description
SARS-CoV-2 3CLpro-IN-19 (Compound C5a) is a non-covalent, non-peptide SARS-CoV-2 3CLpro inhibitor (IC50s: 0.7 μM). SARS-CoV-2 3CLpro-IN-19 has broad-spectrum activity against Omicron subvariants (BA.5, BQ.1.1, and XBB.1.5) infection in human cells, with EC50 values between 30-69 nM[1].
Target Antigen
SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sars-cov-2-3clpro-in-19.html
Solubility
10 mM in DMSO
Smiles
CN(C)C1=CC=C(N(C(CC2=C(C(O)=CC=C3)C3=CN=C2)=O)CC4=CC(Cl)=CS4)C=C1
Molecular Weight
451.97
References & Citations
[1]Pérez-Vargas J, et al. A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants. Emerg Microbes Infect. 2023 Dec;12(2):2246594.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-155186/SARS-CoV-2-3CLpro-IN-19-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-155186/
Clinical Information
No Development Reported
Curated Selection
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