Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

HDAC-IN-62

HDAC-IN-62 (Compound 5) a HDAC inhibitor, with IC50s of 0.78, 1.0, 1.2 μM for HDAC6/8/11 respectively. HDAC-IN-62 inhibits-induced microglial activation by the initiation of autophagy, and inhibits nitric oxide production. HDAC-IN-62 has anti-inflammatory and anti-depressant effects. HDAC-IN-62 inhibits microglial activation in mouse brain[1].

Product Specifications

UNSPSC

12352005

Target

Autophagy; HDAC

Type

Reference compound

Related Pathways

Autophagy; Cell Cycle/DNA Damage; Epigenetics

Applications

COVID-19-anti-virus

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/hdac-in-62.html

Solubility

10 mM in DMSO

Smiles

O=C(/C=C/C1=CC=C(/C=C/C(NO)=O)N1C)C2=CC=CS2

Molecular Formula

C15H14N2O3S

Molecular Weight

302.35

References & Citations

[1]Baek SY, et al. Development of a novel histone deacetylase inhibitor unveils the role of HDAC11 in alleviating depression by inhibition of microglial activation. Biomed Pharmacother. 2023 Aug 9;166:115312.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

FITC Conjugated Rabbit Polyclonal Antibody to Mouse IgG
FA-2361-2 2 mL

FITC Conjugated Rabbit Polyclonal Antibody to Mouse IgG

Sign In for Pricing
View Details
Chrna9 Mouse Gene Knockout Kit (CRISPR)
KN503311 1 Kit

Chrna9 Mouse Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
TARSL2 (Center) Rabbit Polyclonal Antibody
AP18215PU-N 400 µL

TARSL2 (Center) Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
Wnt-C59
TRC-W499300-50MG 50 mg

Wnt-C59

Sign In for Pricing
View Details
2-Biphenylisocyanate
TRC-B397913-500MG 500 mg

2-Biphenylisocyanate

Sign In for Pricing
View Details
PCF11 Antibody
KC-41929-01 50 μL

PCF11 Antibody

Sign In for Pricing
View Details