GLS1 Inhibitor-7
GLS1 Inhibitor-7 (compound 4d) is a GLS1 inhibitor (IC50=46.7 μM), with potential anti-cancer, anti-aging and anti-obesity properties[1].
Product Specifications
UNSPSC
12352005
Target
Glutaminase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/gls1-inhibitor-7.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=C(CNC(CSC2=NN=C(NC(C3=CC=C(C(F)(F)F)C=C3)=O)S2)=O)C=C1
Molecular Formula
C20H17F3N4O3S2
Molecular Weight
482.50
References & Citations
[1]Okada T, et al. Design and structural optimization of thiadiazole derivatives with potent GLS1 inhibitory activity. Bioorg Med Chem Lett. 2023 Sep 1;93:129438.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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