CHBO4
CHBO4 is a potent, reversible, competitive, and selective hMAO-B inhibitor with an IC50 value of 0.031 μM in CHBO subseries and an Ki value of 0.010 ± 0.005 μM. CHBO4 reduce cell damage by scavenging intracellular reactive oxygen species (ROS) . CHBO4 can be used for Parkinson's Disease (PD) research[1].
Product Specifications
CAS Number
98991-32-3
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Monoamine Oxidase; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/chbo4.html
Solubility
10 mM in DMSO
Smiles
BrC1=CC=C(C(/C=C/C2=CC=C(F)C=C2)=O)C=C1
Molecular Formula
C15H10BrFO
Molecular Weight
305.14
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAO-B
Available Sizes
Frequently Asked Questions
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