Eg5-IN-1
Product Specifications
UNSPSC Description
Eg5-IN-1 (compound 6c) is a potent kinesin family motor protein (Eg5) inhibitor with an IC50 value of 1.97 µM. Eg5-IN-1 can be used in research of cancer[1].
Target Antigen
Kinesin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/eg5-in-1.html
Solubility
10 mM in DMSO
Smiles
ClC1=CC=C2C(N=CC=C2NC3=CC=C(C(N/N=C/C4=CC=C(F)C=C4)=O)C=C3)=C1
Molecular Weight
418.85
References & Citations
[1]Ranade SD, et, al. Design, synthesis, molecular dynamics simulation, MM/GBSA studies and kinesin spindle protein inhibitory evaluation of some 4-aminoquinoline hybrids. Comput Biol Chem. 2023 Aug;105:107881.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-155134/Eg5-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-155134/
Clinical Information
No Development Reported
CAS Number
3026790-10-0
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