Eg5-IN-1
Eg5-IN-1 (compound 6c) is a potent kinesin family motor protein (Eg5) inhibitor with an IC50 value of 1.97 µM. Eg5-IN-1 can be used in research of cancer[1].
Product Specifications
CAS Number
3026790-10-0
UNSPSC
12352005
Target
Kinesin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/eg5-in-1.html
Solubility
10 mM in DMSO
Smiles
ClC1=CC=C2C(N=CC=C2NC3=CC=C(C(N/N=C/C4=CC=C(F)C=C4)=O)C=C3)=C1
Molecular Formula
C23H16ClFN4O
Molecular Weight
418.85
References & Citations
[1]Ranade SD, et, al. Design, synthesis, molecular dynamics simulation, MM/GBSA studies and kinesin spindle protein inhibitory evaluation of some 4-aminoquinoline hybrids. Comput Biol Chem. 2023 Aug;105:107881.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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