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Y18501

Y18501 is a oxysterol-binding protein (OSBPI) inhibitor with a similar structure to Oxathiapiprolin. Y18501 shows strong inhibitory activities against Phytophthora spp. and Pseudoperonospora cubensis, with EC50 ranging from 0.0005 to 0.0046 μg/mL. Y18501 shows excellent protective and curative activities against P. cubensis. Y18501 in combination with Chlorothalonil can significantly promote the inhibition of P. cubensis[1].

Product Specifications

CAS Number

2410627-32-4

UNSPSC

12352005

Target

Fungal

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/y18501.html

Solubility

10 mM in DMSO

Smiles

CCC1=NN(CC(N2CCC(C3=NC(C4=NOC(C5=C(F)C=CC=C5F)C4)=CS3)CC2)=O)C6=C1C=CC=N6

Molecular Formula

C27H26F2N6O2S

Molecular Weight

536.60

References & Citations

[1]Wang B, et al. Activity of the new OSBP inhibitor Y18501 against Pseudoperonospora cubensis and its application for the control of cucumber downy mildew. Pestic Biochem Physiol. 2023;194:105415.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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