Antiviral agent 36
Antiviral agent 36 (compound 27) is a potent dengue (DENV) and Zika (ZIKV) viruses inhibitor. Antiviral agent 36 inhibits replication of Zika and dengue virus with EC50s of 100 nM, 90 nM, 210 nM, and 120 nM for ZIKV-FLR, ZIKV-HN16, DENV-2, and DENV-3, respectively[1].
Product Specifications
CAS Number
3033039-89-0
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antiviral-agent-36.html
Solubility
10 mM in DMSO
Smiles
O=C1N(C(/C=C/C2=NC(OC)=CC=C2)=NC3=CC=C(C=C31)N4CCOCC4)C5=CC=CC(C(C)(C)C)=C5
Molecular Formula
C30H32N4O3
Molecular Weight
496.60
References & Citations
[1]Md Ashraf-Uz-Zaman, et al. Quinazolinone Compounds Have Potent Antiviral Activity against Zika and Dengue Virus. J Med Chem. 2023 Aug 10;66 (15) :10746-10760.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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