SARS-CoV-2-IN-54

SARS-CoV-2-IN-54 (Compound 2) is a SARS-CoV-2 inhibitor. SARS-CoV-2-IN-54 has antiviral activity. SARS-CoV-2-IN-54 inhibits SARS-CoV-2 in Vero E6 cells, with an IC50 of 21.4 μM[1].

Product Specifications

UNSPSC

12352005

Target

SARS-CoV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/sars-cov-2-in-54.html

Solubility

10 mM in DMSO

Smiles

O=[N+]([O-])C(C=C1)=CC=C1SC(N2)=C(CC(NC(CCC(CCC(NC(CC3=C(SC4=CC=C([N+]([O-])=O)C=C4)NC5=C3C=CC=C5)C(O)=O)=O)(NC(CN)=O)CCC(NC(C(O)=O)CC6=C(SC7=CC=C([N+]([O-])=O)C=C7)NC8=C6C=CC=C8)=O)=O)C(O)=O)C9=C2C=CC=C9

Molecular Formula

C63H59N11O16S3

Molecular Weight

1322.40

References & Citations

[1]Gargantilla M, et al. C-2 Thiophenyl Tryptophan Trimers Inhibit Cellular Entry of SARS-CoV-2 through Interaction with the Viral Spike (S) Protein. J Med Chem. 2023 Aug 10;66 (15) :10432-10457.