5-HT6 agonist 1
Product Specifications
UNSPSC Description
5-HT6 agonist 1 (Compound 19) is a 5-HT6 agonist (Ki: 5 nM). 5-HT6 agonist 1 has antidepressant-like properties, and improves cognitive deficits. 5-HT6 agonist 1 also inhibits platelet aggregation. 5-HT6 agonist 1 has high metabolic stability[1].
Target Antigen
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/5-ht6-agonist-1.html
Solubility
10 mM in DMSO
Smiles
CCC(C1=NC(N)=NC(N2CCN(C)CC2)=N1)SC3=C(Cl)C=CC(Cl)=C3
Molecular Weight
413.37
References & Citations
[1]Czarnota-Łydka K, et al. Synthesis, computational and experimental pharmacological studies for (thio)ether-triazine 5-HT6R ligands with noticeable action on AChE/BChE and chalcogen-dependent intrinsic activity in search for new class of drugs against Alzheimer's disease. Eur J Med Chem. 2023 Nov 5;259:115695.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-155116/5-HT6-agonist-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-155116/
Clinical Information
No Development Reported
Curated Selection
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