5-HT6 agonist 1
5-HT6 agonist 1 (Compound 19) is a 5-HT6 agonist (Ki: 5 nM) . 5-HT6 agonist 1 has antidepressant-like properties, and improves cognitive deficits. 5-HT6 agonist 1 also inhibits platelet aggregation. 5-HT6 agonist 1 has high metabolic stability[1].
Product Specifications
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/5-ht6-agonist-1.html
Solubility
10 mM in DMSO
Smiles
CCC(C1=NC(N)=NC(N2CCN(C)CC2)=N1)SC3=C(Cl)C=CC(Cl)=C3
Molecular Formula
C17H22Cl2N6S
Molecular Weight
413.37
References & Citations
[1]Czarnota-Łydka K, et al. Synthesis, computational and experimental pharmacological studies for (thio) ether-triazine 5-HT6R ligands with noticeable action on AChE/BChE and chalcogen-dependent intrinsic activity in search for new class of drugs against Alzheimer's disease. Eur J Med Chem. 2023 Nov 5;259:115695.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
21826114 3x 1.0 µg
Gm13718 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)
Sign In for Pricing
View Details 
QS0130Ch-01 48 Tests
Quick Step Chicken salmonella antibody IgM (salmonella- IgM) ELISA Kit
Sign In for Pricing
View Details QS0130Ch-02 96 Tests
Quick Step Chicken salmonella antibody IgM (salmonella- IgM) ELISA Kit
Sign In for Pricing
View Details K6881507 1.0 µg DNA
Cnn3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 2)
Sign In for Pricing
View Details 