HIV-1 inhibitor-59
Product Specifications
UNSPSC Description
HIV-1 inhibitor-59 (Compound I-5b) is a HIV-1 inhibitor, with EC50s of 5.62-171 nM against the wild-type (WT) and mutant HIV-1 strains. HIV-1 inhibitor-59 has moderate RT enzyme inhibitory activity (IC50: 0.094-12.0 μM)[1].
Target Antigen
HIV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/hiv-1-inhibitor-59.html
Solubility
10 mM in DMSO
Smiles
N#CC1=CC(C)=C(OC2=C(F)C=C(C#N)C(NC3CCN(CC4=CC=C(S(C)(=O)=O)C=C4)CC3)=N2)C(C)=C1
Molecular Weight
533.62
References & Citations
[1]Song H, et al. 5-Cyano substituted diarylpyridines as potent HIV-1 NNRTIs: Rational design, synthesis, and activity evaluation. Eur J Med Chem. 2023 Nov 5;259:115686.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-155114/HIV-1-inhibitor-59-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-155114/
Clinical Information
No Development Reported
Curated Selection
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