DNA polymerase-IN-2

DNA polymerase-IN-2 (Compd 3c), a coumarin derivative, exhibits inhibitory activity against Taq DNA polymerase with IC50 of 48.25 μM , which can be used in value-added disease research[1].

Product Specifications

CAS Number

[2953023-80-6]

UNSPSC

12352005

Target

DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/dna-polymerase-in-2.html

Solubility

10 mM in DMSO

Smiles

CC(OC(C=C1O2)=CC=C1C(CSC(C)=O)=CC2=O)=O

Molecular Formula

C14H12O5S

Molecular Weight

292.31

References & Citations

[1]Ezequiel F Bruna-Haupt, et al. Synthesis of Structurally Related Coumarin Derivatives as Antiproliferative Agents. ACS Omega. 2023 Jul 13;8 (29) :26479-26496.