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BRD4 Inhibitor-27

BRD4 Inhibitor-27 (compound 6) is a BRD4 inhibitor with IC50 of 9.6 and 11.3 μM for BRD4 BD1 and BRD4 BD2, respectively. BRD4 Inhibitor-27 has the potential to study cancer[1].

Product Specifications

CAS Number

930039-92-2

UNSPSC

12352005

Hazard Statement

H315-H319-H320

Target

Epigenetic Reader Domain

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/brd4-inhibitor-27.html

Solubility

10 mM in DMSO

Smiles

FC(F)(C1=NN=C2C=CC(NCCC3=CNC4=C3C=CC=C4)=NN21)F

Molecular Formula

C16H13F3N6

Molecular Weight

346.31

Precautions

P264-P280-P302+P352-P305+P351+P338-P362

References & Citations

[1]Kim JH, et al. Crystal structure of [1,2,4] triazolo[4,3- b ]pyridazine derivatives as BRD4 bromodomain inhibitors and structure–activity relationship study . Sci Rep 13, 10805 (2023) .

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

BD1; BD2

Available Sizes

Frequently Asked Questions

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