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SARS-CoV-2 Mpro-IN-7

SARS-CoV-2 Mpro-IN-7 (compound 6g) is a potent inhibitor of Mpro-SARS-CoV-2 (IC50=8.8 μM, CC50=10 μM) [1].

Product Specifications

UNSPSC

12352005

Target

SARS-CoV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/sars-cov-2-mpro-in-7.html

Solubility

10 mM in DMSO

Smiles

O=C1[C@@]2([C@]3(C(C=CC=C4)=C4NC3=O)N(C)C[C@]2(C5=CC=C(Br)C=C5)[H])CN(P(OCC)(OCC)=O)C/C1=C\C6=CC=C(Br)C=C6

Molecular Formula

C33H34Br2N3O5P

Molecular Weight

743.42

References & Citations

[1]Bekheit MS, et al. Spiroindole-containing compounds bearing phosphonate group of potential Mpro-SARS-CoV-2 inhibitory properties. Eur J Med Chem. 2023 Oct 5;258:115563.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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