Antiproliferative agent-26
Antiproliferative agent-26 (compound 4g) is an antiproliferative agent with much broad range of activity targeting Leukemia, CNS, Melanoma, Renal and Breast (at the concentration of 10 μM) . Antiproliferative agent-26 inhibits colony forming and arrests cell cycle at G1 phase/S phase at 5 μM and 25 μM, respectively[1].
Product Specifications
CAS Number
9007-83-4
UNSPSC
12352005
Target
Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antiproliferative-agent-26.html
Solubility
10 mM in DMSO
Smiles
O=C(C)C1=C(C)NC2=C1C(C3=CC=C(OCO4)C4=C3)=NC5=C2C=CC=C5
Molecular Formula
C21H16N2O3
Molecular Weight
344.36
References & Citations
[1]Mingoia F, et al. Synthesis of new antiproliferative 1, 3, 4-substituted-pyrrolo [3, 2-c] quinoline derivatives, biological and in silico insights[J]. European Journal of Medicinal Chemistry, 2023: 115537..
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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