Antiproliferative agent-26

Antiproliferative agent-26 (compound 4g) is an antiproliferative agent with much broad range of activity targeting Leukemia, CNS, Melanoma, Renal and Breast (at the concentration of 10 μM) . Antiproliferative agent-26 inhibits colony forming and arrests cell cycle at G1 phase/S phase at 5 μM and 25 μM, respectively[1].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352005

Target

Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/antiproliferative-agent-26.html

Solubility

10 mM in DMSO

Smiles

O=C(C)C1=C(C)NC2=C1C(C3=CC=C(OCO4)C4=C3)=NC5=C2C=CC=C5

Molecular Formula

C21H16N2O3

Molecular Weight

344.36

References & Citations

[1]Mingoia F, et al. Synthesis of new antiproliferative 1, 3, 4-substituted-pyrrolo [3, 2-c] quinoline derivatives, biological and in silico insights[J]. European Journal of Medicinal Chemistry, 2023: 115537..