BDM91514
BDM91514 improves antibiotic potency through AcrB inhibition. BDM91514 prevents the growth of E. coliBW25113 (EC90: 8 μM) in the presence of 8 μg/mL Pyridomycin. BDM91514 has suitable plasma and microsomal stability[1].
Product Specifications
CAS Number
[2892824-90-5]
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/bdm91514.html
Solubility
10 mM in DMSO
Smiles
ClC1=C(N2CCNCC2)N=CC(C3=NOC(CCN)=N3)=C1.Cl.Cl
Molecular Formula
C13H19Cl3N6O
Molecular Weight
381.69
References & Citations
[1]Compagne N, et al. Optimization of pyridylpiperazine-based inhibitors of the Escherichia coli AcrAB-TolC efflux pump. Eur J Med Chem. 2023 Jul 7;259:115630.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-155047/BDM91514-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-155047/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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