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Antihypertensive agent 3

Antihypertensive agent 3 (compound 4a) is an antagonis of angiotensin II receptor 1. Antihypertensive agent 3 exhibits antihypertensive activity in a spontaneously hypertensive rats (SHRs) model[1].

Product Specifications

CAS Number

9007-83-4

UNSPSC

12352005

Target

Angiotensin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/antihypertensive-agent-3.html

Solubility

10 mM in DMSO

Smiles

O=C(O)C1=C(C2=CC=CC=C2)N(S(C)(=O)=O)C3=CC=CC=C31

Molecular Formula

C16H13NO4S

Molecular Weight

315.34

References & Citations

[1]Danilenko AV, et al. Design, synthesis and biological evaluation of novel indole-3-carboxylic acid derivatives with antihypertensive activity. Bioorg Med Chem Lett. 2023 Jun 15;90:129349.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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