Antihypertensive agent 2

Antihypertensive agent 2 (Compound 4g) is an antihypertensive agent. Antihypertensive agent 2 has effective antagonistic activities against angiotensin II receptor 1. Antihypertensive agent 2 reduces the blood pressure with equal or more potency compared to Losartan (HY-17512) [1].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352005

Target

Angiotensin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/antihypertensive-agent-2.html

Solubility

10 mM in DMSO

Smiles

O=C(O)C1=C(C2=CC=CC=C2)N(C(C3=CC=CC=C3)=O)C4=CC=CC=C41

Molecular Formula

C22H15NO3

Molecular Weight

341.36

References & Citations

[1]Danilenko AV, et al. Design, synthesis and biological evaluation of novel indole-3-carboxylic acid derivatives with antihypertensive activity. Bioorg Med Chem Lett. 2023 Jun 15;90:129349.