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VE-PTP-IN-1

VE-PTP-IN-1 (compound 2) is a weakly acidic and selective inhibitor of vascular endothelial protein tyrosine phosphatase (VE-PTP) .VE-PTP-IN-1 is assocaited with vascular homeostasis and angiogenesis.

Product Specifications

UNSPSC

12352005

Target

Phosphatase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ve-ptp-in-1.html

Solubility

10 mM in DMSO

Smiles

OC(C1=NOC(C2=CN(C)C3=CC=CC=C23)=C1CO)=O

Molecular Formula

C14H12N2O4

Molecular Weight

272.26

References & Citations

[1]Asano W, et al. Fragment-Based Discovery of Novel VE-PTP Inhibitors Using Orthogonal Biophysical Techniques. Biochemistry. 2023 Jul 18;62 (14) :2161-2169.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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