PHA-690509
PHA-690509 is an anti-ZikV compound that inhibits ZikV replication. PHA-690509 is also a CDK inhibitor, and inhibits caspase-3 activity[1][2].
Product Specifications
CAS Number
[492445-28-0]
UNSPSC
12352005
Target
Caspase; CDK; Flavivirus
Type
Reference compound
Related Pathways
Anti-infection; Apoptosis; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/pha-690509.html
Solubility
10 mM in DMSO
Smiles
C[C@@H](C1=CC=C(NC(C)=O)C=C1)C(NC2=NC=C(C(C)C)S2)=O
Molecular Formula
C17H21N3O2S
Molecular Weight
331.43
References & Citations
[1]Devillers J. Repurposing drugs for use against Zika virus infection. SAR QSAR Environ Res. 2018 Feb;29 (2) :103-115.|[2]Alam A, et al. Recent trends in ZikV research: A step away from cure. Biomed Pharmacother. 2017 Jul;91:1152-1159.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-15503/PHA-690509-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-15503/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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