sEH inhibitor-16
Product Specifications
UNSPSC Description
sEH inhibitor-16 is a soluble epoxide hydrolase (sEH) inhibitors with an IC50 of 2 nM. sEH inhibitor-16 reduces the inflammatory damage in Cerulein (HY-A0190)-induced acute pancreatitis (AP) in mice and can be used for inflammation/immunology research[1].
Target Antigen
Epoxide Hydrolase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/seh-inhibitor-16.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC2=C(N(CC3=CC=C(C(C)C)C=C3)C=C2)C=C1)NCC4(C5)C[C@H](C[C@H]5C6)C[C@H]6C4
Molecular Weight
455.63
References & Citations
[1]Musella S, et.al. Design, Synthesis, and Pharmacological Characterization of a Potent Soluble Epoxide Hydrolase Inhibitor for the Treatment of Acute Pancreatitis. J Med Chem. 2023 Jul 13;66(13):9201-9222.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-155029/sEH-inhibitor-16-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-155029/
Clinical Information
No Development Reported
CAS Number
2999636-75-6
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
