HAT-IN-8
HAT-IN-8 (Compound 38) is a BBB-penetrable T. brucei inhibitor (EC50: 0.18 μM) . HAT-IN-8 can be used for the research of Human African trypanosomiasis[1].
Product Specifications
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/hat-in-8.html
Solubility
10 mM in DMSO
Smiles
CC(C)(O)CC(C1=C(N)N=C(NC2=CC=C(F)C(F)=C2)S1)=O
Molecular Formula
C14H15F2N3O2S
Molecular Weight
327.35
References & Citations
[1]Cleghorn LAT, et al. Development of a 2,4-Diaminothiazole Series for the Treatment of Human African Trypanosomiasis Highlights the Importance of Static-Cidal Screening of Analogues. J Med Chem. 2023 Jul 13;66 (13) :8896-8916.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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