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HAT-IN-8

HAT-IN-8 (Compound 38) is a BBB-penetrable T. brucei inhibitor (EC50: 0.18 μM) . HAT-IN-8 can be used for the research of Human African trypanosomiasis[1].

Product Specifications

UNSPSC

12352005

Target

Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/hat-in-8.html

Solubility

10 mM in DMSO

Smiles

CC(C)(O)CC(C1=C(N)N=C(NC2=CC=C(F)C(F)=C2)S1)=O

Molecular Formula

C14H15F2N3O2S

Molecular Weight

327.35

References & Citations

[1]Cleghorn LAT, et al. Development of a 2,4-Diaminothiazole Series for the Treatment of Human African Trypanosomiasis Highlights the Importance of Static-Cidal Screening of Analogues. J Med Chem. 2023 Jul 13;66 (13) :8896-8916.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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