Apoptosis inducer 13

Apoptosis inducer 13 (Compound Ru4) can induce cancer cell apoptosis, and inhibits cancer cell migration and invasion. Apoptosis inducer 13 converts coenzyme NADH to NAD+, and increases intracellular ROS levels[1].

Product Specifications

UNSPSC

12352005

Target

Apoptosis; Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/apoptosis-inducer-13.html

Solubility

10 mM in DMSO

Smiles

F[P-](F)(F)(F)(F)F.Cc1c(C)c(C)c(C)c(C)c1C.O=C(C2=C3C(C4=C(NC(C5=CC=CC=C5)(C6=CC=CC=C6)N7)C7=C38)=C(C(N(CCCC)C4=O)=O)C9=C2N=C%10C(C%11=CC=C[N]%12=C%11C(C%10=CC=C%13)=[N]%13[Ru+]%12(Cl)[])=N9)N(CCCC)C8=O

Molecular Formula

C59H54ClF6N8O4PRu

Molecular Weight

1220.60

References & Citations

[1]Yang Y, et al. Naphthalene Diimide-Functionalized Half-Sandwich Ru (II) Complexes as Mitochondria-Targeted Anticancer and Antimetastatic Agents. Inorg Chem. 2023 Jun 19;62 (24) :9649-9660.