Apoptosis inducer 13
Product Specifications
UNSPSC Description
Apoptosis inducer 13 (Compound Ru4) can induce cancer cell apoptosis, and inhibits cancer cell migration and invasion. Apoptosis inducer 13 converts coenzyme NADH to NAD+, and increases intracellular ROS levels[1].
Target Antigen
Apoptosis; Reactive Oxygen Species
Type
Reference compound
Related Pathways
Apoptosis;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/apoptosis-inducer-13.html
Solubility
10 mM in DMSO
Smiles
F[P-](F)(F)(F)(F)F.Cc1c(C)c(C)c(C)c(C)c1C.O=C(C2=C3C(C4=C(NC(C5=CC=CC=C5)(C6=CC=CC=C6)N7)C7=C38)=C(C(N(CCCC)C4=O)=O)C9=C2N=C%10C(C%11=CC=C[N]%12=C%11C(C%10=CC=C%13)=[N]%13[Ru+]%12(Cl)[])=N9)N(CCCC)C8=O
Molecular Weight
1220.60
References & Citations
[1]Yang Y, et al. Naphthalene Diimide-Functionalized Half-Sandwich Ru(II) Complexes as Mitochondria-Targeted Anticancer and Antimetastatic Agents. Inorg Chem. 2023 Jun 19;62(24):9649-9660.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-155023/Apoptosis-inducer-13-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-155023/
Clinical Information
No Development Reported
Curated Selection
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