AChE-IN-30
AChE-IN-30 is an AChE inhibitor with an IC50 value of 4.4 μM. AChE-IN-30 has neuroprotective activity, and inhibits H2O2-induced apoptosis by suppressing intracellular ROS accumulation. AChE-IN-30 can be used for research of Alzheimer's disease[1].
Product Specifications
CAS Number
[2937454-22-1]
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ache-in-30.html
Purity
98.71
Solubility
DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
NC1=CC=C(NC2=C(NC3CCN(CC4=CC=CC=C4)CC3)C(C2=O)=O)C=C1
Molecular Formula
C22H24N4O2
Molecular Weight
376.45
References & Citations
[1]Wan D, et al. Design, Synthesis, and Biological Activity of Donepezil: Aromatic Amine Hybrids as Anti-Alzheimerss Drugs. ACS Omega. 2023 Jun 5;8 (24) :21802-21812.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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